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The study investigates the antibacterial activity of leaves ethanolic extract of Azadirachta indica on human uro-pathogens that having the ability to cause urinary tract infections. The extract screened for S. aureus, E.coli and P. aeruginosa, for their antimicrobial efficiency. For this purpose, MIC, MBC and antibiotic sensitivity test were performed. Zones were appeared in agar well-containing leaf extract as compared to sensitivity test. The difference between MIC and MBC at tube 4 neem show the activity against E. coli and P. aeruginosa while for S. aureus results showed the inhibitory effect. The phytochemical analysis shows that neem has components which enhance the antimicrobial activity of neem. Phytochemical screening of neem not only having antimicrobial activity but also have antifungal, antiviral properties this activity of neem comes due to its bitter taste and the taste is due to the presence of components likes alkaloids, flavonoids, triterpenes. In current era the antibiotics therapies are more risky to cure infection because antibiotics has vast side effects that directly effects the certain body parts mainly kidney, stomach, upper and lower respiratory tract not only effects but also cause respective body organs disorder So, to subside the effects of antibiotics we are now able to cure microbial infections by the use of herbal medicine. In which NEEM has played a vital role to cure both infections skin as well as inner body infections.
Keywords: Azadirachta indica; MIC; MBC; Phytochemical analysis; antimicrobial activity