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Staphylococcus aureus causing wide spectrum of infections and has tendency for the development of multidrug resistance. The study was conducted to find out the antibiogram of S. aureus from clinical samples at Ayub Teaching institute, Abbottabad since September 2018 to May 2019 and to determine the prevalence of MRSA and MSSA .Total 100 Staphylococcus aureus was collected from clinical samples (pus, urine and blood) and identification was done by standard microbiological methods and antibiotic susceptibility testing was done by using disk diffusion method as per CLSI guidelines. Out of these 100 isolates, 44 (44%) were MRSA and 56 (56%) were MSSA. Most of the MRSA isolates were collected from blood 20(45.45%) followed by pus 14(31.81%) and urine 10 (22.7%) correspondingly while the highest prevalence of MSSA was in pus samples 26 (46.42%), and were same in the samples of blood and urine 15 (26.78%). MRSA was sensitive to Amikacin (95%) and Vancomycin (86%) but resistant to Oxacillin (100%) and Imipenem (82%). MSSA was sensitive to Oxacillin (100%) and Doxycyclin (86%) but resistant to Ciprofloxacin and Oflaxacin (64%). All the isolates were sensitive to Amikacin, Doxycyclin and Gentamicin .Frequency of S.aureus is common in clinical samples of patients at Abbottabad and these were momentously resistant to frequently prescribed antibiotics, so, anti-staphylococcal antibiotics correct use is crucial.
Keywords: Methicillin resistant Staphylococcus aureus; Methicillin sensitive Staphylococcus aureus; Susceptibility; Staphylococcus aureus prevalence