5. Antibiotic susceptibility pattern of bacterial strains isolated from different clinical samples in Multan, Pakistan

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Hafsa Alam and Humaira Yasmeen


Rapid evolution of resistance in bacteria towards antibiotics has dramatically become a global health crisis. The aim of present study was to check the prevalence and antimicrobial sensitivity of bacteria present in clinical samples. Two hundred and seventy different clinical samples were examined in laboratory of the Chaudhary Pervaiz Elahi Institute of Cardiology, Multan Pakistan. Clinical isolates were isolated on MacConkey agar, blood agar and Cystine Lactose Electrolyte Deficient Agar (CLED Agar). The isolated strains were tested for antimicrobial susceptibility against the panel of 27 antibiotics. Out of 270 sample, 91(33.7%) showed microbial load. Staphylococcus aureus, Pseudomonas spp., Escherichia coli, Klebsiella spp. and Candida spp. were commonly isolated. Staphylococcus aureus showed the highest prevalence as monoresistant and polyresistant strain. The malpractice of self-medication with unrestricted supply of medicines have played an important role in antimicrobial resistance.

Keywords: Antimicrobial resistance; Escherichia coli; ESBL; Zone of inhibition


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