30. Sero prevalence of Hepatitis B Virus (HBV) in general population of Lakki Marwat, Khyber Pakhtunkhwa-Pakistan

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Muhammad Ishaq Shah and Zia Ur Rahman Awan

Abstract

A research study was conducted with the aim to investigate the frequency of Hepatitis B Virus positivity in the general population of district Lakki Marwat. Blood samples were collected from 2000 individuals in various hospitals and diagnostic/ medical laboratories of the study area. All the blood samples were evaluated for HBV by Liver function tests (LFTs), Immuno-chromatographic tests (ICT) and PCR. Among the total, 108 blood samples were found positive for the virus with a prevalence rate of 5.4%. A higher prevalence rate (4.15%) was found in males as compare to 1.25% in females. Among the total HBV positive samples 83 (76.85%) were male (from 4 years to 75 years) and 25 (23.19%) were female (from 5 years to 60 years). The HBV positive data was also analyzed for various age groups i.e. 1-15 years, 16-30 years, 31-45 years, 46-60 years and above 60 years. It was found that disease prevails more in males than in females and is predominant in the age group 16-30 (57%), followed by age groups 31-45 (23%),  1-15 (10.18%), 46-60 (7%) and >60 (3%) respectively. Various risk factors were found involved in the spread of HBV in the study area like medical injections (59.26%), dental procedures by medical quacks (12.04%), hair dressing and shaving salons/ barber shops (11.11%), transfusion of blood and blood based products (5.56%), mother to children transmission (3.70%), occupational risk groups (2.78%), sexual transmission (2.78%), tattooing (0.92%), circumcision (0.92%) and shared injection by drug abuser (0.92%).


Keywords: Frequency; HBV; ICT; PCR; Risk factors


http://dx.doi.org/10.19045/bspab.2020.90267


 

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