23. Phytochemical analysis and in-vitro anti-bacterial and anti-fungal activity of Verbascum arianthum (Benth)

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Aqsa Tariq, Ghulam Mujtaba Shah, Ahmad Zada, Ahmad Ali, Amir Zaman Shah, Iqra Fatima

Abstract

The current research work is to investigate phytochemicals profile of Verbascum arianthum and anti-microbial activity of crude extract. The results showed that Verbascum arianthum contains various important phytochemical like, Flavonoids, Phenols, Quinones, Steroids, Saponins, Tannins, alkaloids, Carbohydrates and Cumarine. To check the antimicrobial activity four bacterial strains as, Escherichia coli, Salmonella typhi, Methicillin resistant staphylococcus aureus, and Pseudomonas aeruginosa were used following agar-well diffusion method. The observed results showed highly significant ant-bacterial activity and among the different extract the leaves methanolic extract are better than stem and root extract against our tested bacterial stains. The extract also tested for antifungal activity and result indicated that the leaves and stem methnolic extract showed highly significant antifungal activity against Aspergilus Niger. Previously the others species of genus Verbescum were screened and found potential antimicrobial activities but Verbascum arianthum was not studied previously so this is the first report on the pharmacognostic studies of Verbascum arianthum and is helpful in the characterization of the crude drug.


Keywords: Antimicrobial Activity; Aspergilus Niger; Phytochemicals; Verbascum Arianthum


http://dx.doi.org/10.19045/bspab.2021.100082

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