46. Stem cells perspective in cure and management of diabetic retinopathy
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Abstract
Diabetic retinopathy is the trending issue of the vision loss worldwide that occurs due to mismanagement of glycemic level of the diabetic patients. In diabetic retinopathy neurons and capillaries, which are associated with retina, start to damage that result in alteration in the vision function of retina. Long term effective strategy for diabetic retinopathy has not been proposed yet but the stem cells can make it possible to prevent or cure diabetic retinopathy. Stem cells have the potential of repairing and replacement of damaged or defected retinal cells. Different types of stem cells like induced pluripotent stem cells, mesenchymal stem cells, some other factors like CD34+ cells, HLA factors etc have a significant role in the treatment of diabetic retinopathy. In this review, other than the role of stem cells, we have discussed the management and screening of diabetic retinopathy. Management and screening, are the parts of the strategy to reduce the risk of diabetic retinopathy that act like the tools to treat diabetic retinopathy. As stem cells are the most feasible source of treatment of diabetic retinopathy. Management and screening of diabetic retinopathy at early stage could be helpful in treatment even when the patient doesn’t show symptoms. The stem cell therapy in diabetic retinopathy offers a long lasting treatment option.
Keywords: CD34+ cells; Diabetic retinopathy; HLA factors; Induced pluripotent stem cells; Mesenchymal stem cells