1. Prospective therapeutic strategies of microbiome engineering and human metagenome manipulation: A mini review
Abstract
Gut microbiota is a complex ecosystem with a unique diversity of microorganisms living in the digestive tracts of humans and animals and has a strong impact on human health. This microbial relationship plays a crucial role in the metabolic health of the human host. Any dysbiosis in this relationship causes various metabolic, immunological, neoplastic, and functional diseases. For the proper maintenance of relationships between gut microbiota, health, and disease, a few strategies including the use of probiotics/prebiotics, antibiotics, fecal microbial transplant, and drug targeting have been used. Gut microbiota management strategies in balance with dietary modifications signify an interesting field of research, however, associated data along with a deeper understanding is mandatory for the improvement of more targeted and specified therapeutic strategies. In this review, we will address the exciting potential, emerging challenges, and current directions in human microbiome engineering strategies. Additionally, this review analyzes the significance and use of microbiome engineering for the improvement of human health.
Keywords: Antibiotics; Diet; Gut microbiota; Prebiotics; Probiotics; Microorganisms
