56. Analysis of antibacterial activity of indigenous Mirabilis jalapa, Solanum nigrum and Aloe vera

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Rameez Nisar, Raja Tahir Mahmood, Ansar Ahmed Abbasi, Khan Muhammad, Khalid Hameed Muhammad Asghar Khan, Tauqeer Ahmed Mughal, Saiqa Khushal, Rabia Shaukat, Maleeha Masood

Abstract

In this study, the antimicrobial potential of medicinal plants was determined against three gram-negative: Klebsiella pneumonia, Pseudomonas aeruginosa and Escherichia coli, and four gram-positive bacteria: Streptococcus pyogenes, Bacillus subtilis, Enterococcus and Staphylococcus aureus. Aqueous extracts of three medicinal plants namely Mirabilis jalapa, Solanum nigrum and Aloe vera were used to check the antimicrobial activity. The antimicrobial potential of these plants was determined by agar well diffusion method. The antimicrobial activity of aqueous extract of Aloe vera was better than Solanum nigrum, followed by Mirabilis jalapa which exhibited lesser activity. Maximum zone of inhibition was shown by K. pneumonia 22 mm at 100 µL concentration for A. vera extract. The was no antibacterial activity against B. subtilis and Enterococcus by A. vera. Maximum zone of inhibition was exhibited by K. pneumoniae   and B.  subtilis 20 mm at 100 µL concentrations of M. jalapa. The Enterococcus, S.  pyogenes and P. aeruginosa did not show any result against M. jalapa extract. The highest zone of inhibition was exhibited by S. pyogenes 17 mm at 100 µL concentration. E. coli and K. pneumoniae did show any activity against plant.  


Keywords: Antibacterial activity; A. vera; B. subtilis; Medicinal Plants; S. nigrum


http://dx.doi.org/10.19045/bspab.2023.120070

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