Prevalence of urinary tract infections and antibiotic effectiveness against uropathogens among females of different ages in Dera Ismail Khan, Khyber Pakhtunkhwa-Pakistan

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Anila Khan, Atta Ur Rehman, Shumaila Noreen Malik, Muhammad Inamullah Malik, Faiqah Ramzan, Habibullah, Ambrina Tariq Saqib Ali Rustam, Ghulam Jilani, Muhammad Zeeshan


Infections of Urinary system are predominant worldwide and the incidence of these infections is more serious in developing countries like Pakistan. The incidence of UTIs, causative organisms and resistance developed in pathogen due to continuous usage of conventional antibiotic was investigated in one of the remote area of Pakistan. The urine samples of females were collected from three groups on the basis of age and primed to screen out positive samples having infection and pus cells. Moreover, the pus cells containing urine samples were then cultured and biochemical tests were completed to characterize the causative pathogens. Afterwards, the resistance against different antibiotics was studied by smearing antibiotics on specified culture media. The percentage of positive samples was recorded high in females of young age (15 to 30 years). Several strains of bacteria were identified for example E. coli, Klebseilla spp: Pseudomonas aeruginosa and enterococcus ssp. The lavish use of orthodox antibiotics including Ampicillin, Tetracycline, Ciprofloxacin and Amoxicillin showed resistance against pathogen. Ceftriaxone, Amikacin, Imipenem and Fosfomycin meaningfully demonstrated their efficacy to control the bacterial species responsible for urinary tract infections in female of district Dera Ismail Khan, KP, Pakistan. The careful use of specific antibiotics can successfully control the Urinary Tract Infections in female.

Keywords: Antibiotics; Culturing, Urinary tract infection; Uropathogens

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