Chemical composition, anti-bacterial and anti-fungal activity of essential oil of Nannorrhops ritchiana growing wild in district Kech, Balochistan
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Abstract
Essential oils from leaves of Nannorrhops ritchiana growing wild in District Kech was for the first time analyzed for chemical components through gas chromatography mass spectroscopy (GC-MS) and screened for antimicrobial activity. Total 6 chemical compounds were identified in extracted essential oil composition of N. ritchiana. Eucalyptol (1.63%), Endo-Borneol (3.24), Cyclohexanone, 5-methyl-2-(1-methylethylidene) (3.84%), 7-Oxabicyclo [4.1.0] heptan-2-one 6-methyl-3-(1-methylethyl)- (53.26%), Bicyclo [3.1.1] hept-3-en-2-one, 4,6,6-trimethyl- (21.61%), and 3-Cyclopenten-1-one, 2-hydroxy-3-(3-methyl-2-butenyl)-(16.70%) respectively. 7-Oxabicyclo [4.1.0] heptan-2-one 6-methyl-3-(1-methylethyl)- was the major component found in extracted essential oil. The antimicrobial activity of essential oil was tested against two bacterial strains: the gram negative Escherichia coli and the gram positive Staphylococcus aureus and three fungal strains Candida albicans, Candida glabrata and Candida tropicalis. Essential oil showed a significant activity against the bacterial and fungal strains that may provide promising pharmaceutical profits.
Keywords: Anti-bacterial; Anti-fungal; essential oil; Nannorrhops ritchiana