31. Configuration of dyslipidemia in patients with type 2 diabetes mellitus visiting tertiary care hospital Quetta-Pakistan

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Shabbir Hussain Shah, Muhammad Masood Tariq kiani, Muhammad Aleem Akhter Tahir Hameed, Farhat abbas Bokhari, Zafarullah Khan, Babar Hilal Ahmed Muhammad Yousaf Abdul Salam Shah Wardha Shamim Lodhi Hina Ishtiaq Noor ul Hassan, Anwar ur Rehman

Abstract

Abstract


Dyslipidemia among others, is the profound threat for cardiovascular disorder in Type 2 Diabetes Mellitus (DM). Prompt recognition and management of dyslipidemia in Type 2 DM can inhibit threats for atherogenic heart disease. The motivation behind the upcoming study was to uncover the irregularity of lipid profiles in Type 2 DM patients. Requisite statistics were taken from 242 patients (95 females, 147 male) suffering with Type 2 DM and registered in the Department of Endocrinology and Medicine at Bolan Medical Complex hospital (BMCH) and Sandeman Provincial Hospital (SPH) Quetta, Pakistan. The Result of lipid profiles indicated that statistical values for Total Cholesterol (TC), Triglyceride (TG), High Density Lipid Cholesterol (HDL-C), Low Density Lipid Cholesterol (LDL-C) and Very Low Density Lipid Cholesterol were (VLDL-C) 196.03 ± 67.99, 256.69 ±173.56, 36.11 ±9.95,118.29 ± 56.41 and 49.80  ± 33.44 mg/dl in female subjects respectively. In male subjects the mean-values for TC, TG, HDL-C, LDL-C and VLDL-C were 222.12 ± 69.24, 339.37 ± 260.73, 34.73 ± 7.10, 119.08± 42.10 and 68.46 ± 54.42 mg/dl respectively. FPG demonstrated profoundly positive correlation with RPG. TG displayed a profoundly negative correlation with HDL, while positive correlation with VLDL, but HDL showed negative statistical correlation with LDL. The study disclosed communal lipid irregularities during diabetes prompted dyslipidemia i.e., elevated TC, TG, LDL-C and decreased HDL-C values. This abstraction advocates prevalence of hyperlipidemia over increased dominance of dyslipidemia.


Keywords: Cardiovascular disorders; Dyslipidemia; Type 2 diabetes mellitus


http://dx.doi.org/10.19045/bspab.2018.700187

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