67. Biological and electronic transition studies of the previously reported organotin (IV) dithiocarbamates of p-Fluoro-Nmethylbenzylaminedithiocarbamate

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Abdul Ghaffar, Naqeebullah Khan, Samiullah, Irshad Ali Ali Akbar Attiq-ur-Rehman, Waheed Ahmed Shah, Abdul Baqi, Saifullah



Four organotin(IV) complexes of p-Fluro-N-methylbenzylaminedithiocarbamate with general formula R2SnL2 where (R= dimethyl, diphenyl and dibutyl)and R3SnL (R = triphenyl) synthesized earlier in the group were tested for their bioactivity. Antibacterial assay against four Gram-negative and Gram-positive strains including Salmonella typhi, Escherichia coli, Pneumoniae and Staphylococcus aureus, while antifungal activity against Aspergillus Niger of the compounds were carried out using standard procedures.The tested compounds were found significantly active against Aspergillus Niger. Whereas, the antibacterial activity of compounds wasfound moderate as compared to their antifungal activities.

Keywords: Disc diffusion method; 1H NMR; Organotin dithiocarbamates


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