18. Evaluation of the antibacterial and antifungal potential of spider saxifrage plant (Saxifraga flagellaris Willd.)

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Khushnood ur Rehman, Sher Wali, Naveed Akhtar, Barkat Ullah Sumera Afzal Imtiaz Ahmad Muhammad Hamayun

Abstract

The current research work was performed to find antifungal and antibacterial potential of spider saxifrage plant. The aim was to find a new source against the selected pathogenic bacterial and fungal strains. Saxifraga flagellaris extract was fractionated. Five fractions were prepared and tested for antimicrobial potential against the selected fungal and bacterial strains. The highest antifungal activity (35-65%) was displayed by the crude methanolic extract against all the selected fungal stains and the lowest antifungal trend was exhibited by the aqueous fraction. However in antibacterial activity the n-hexane fraction showed maximum antibacterial activity (46-48%) against the selected pathogens and more or less same trend was followed by crude methanolic extract, while the least inhibition was shown by aqueous fraction. The other fractions though remained with moderate zone of inhibition but were significant.


Keywords: Antibacterial; Antifungal; Inhibition; Spider Saxifrage; Saxifraga flagellaris


http://dx.doi.org/10.19045/bspab.2019.80058

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