2. Virulence factors and drug resistance in Klebsiella pneumoniae; an emerging superbug

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Faiza Liaqat, Wajeeha Naeem Muhammad Shafee Muhammad Anwar Haleema Sadia Daud Ghilzai Ali Akbar


Klebsiella pneumoniae is a nosocomial pathogen usually concerned in hospital out‐ breaks with a propensity for antibiotic resistance (ABR) to support β-lactam antibiotics and several other antimicrobial classes. The effective feast, spread and infection of the Gram-negative bacterium can be credited to an innumerable of influences comprising host, environmental, virulence factors and a vast diversity of ABR mechanisms. The poor handling consequences and insufficient treatment options are significances of the effective pathogenesis and spread of ABR in the increasingly common in Klebsiella pneumoniae bacterium which producing β-lactamase. This is a comprehensive literature review on Klebsiella exploring all the drug resistance and pathogenicity related issues associated with this bug, it will provide a roadmap to the researcher for further research extension in this field. 

Keywords: Antibiotics; Public health; Pathogenicity; Superbugs; Virulence factor


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